Single Nucleotide Polymorphism Spectral Decomposition Lite (SNPSpDlite)
SNPSpDlite takes the same input at SNPSpD, but ONLY outputs the LD correlation matrix, Meff and MeffLi estimates and GOLD input (i.e., does not perform time-consuming varimax/promax rotations) thus allowing users to obtain Meff/MeffLi values for large numbers (1000s) of SNPs.
Users may also be interested in the related site (SNPSpDsuperlite) which is an even leaner version of SNPSpD.
Users may also be interested in the related site (matSpD) which only requires users to upload a correlation matrix.
Please use the following reference when
reporting results based on SNPSpD:
Nyholt
DR (2004) A simple correction for multiple testing for SNPs in linkage
disequilibrium with each other. Am J Hum Genet 74(4):765-769.
To run SNPSpD using all fully genotyped
family members:
To run SNPSpD using all family members:
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